Long ago, a war broke out in Japan that pitted Kantou against Kansai and divided the country. Kansai became dependent on Kantou, but slowly the police and government began losing control of Kansai to criminals known as Akudama.

Tomoro Tenma lives in a world where human thoughts and emotions, known as e-Pulse, power AI devices called Sapotama. But when Digimon begin materializing from Sapotama and feeding on e-Pulse, society begins to fracture.

Follows Rouge, an android girl, who is on a mission on Mars with her partner Naomi. The mission is to murder Immortal Nine, nine artificial humans who are hostile to the government.