Jane Vasko was an undercover police officer attempting to infiltrate a major New York City drug ring. After gaining the trust of the dealers, her cover was unknowingly blown and she was forced to submit to a drug cocktail that landed her in a coma - until one day she awoke to a world where nothing was the same! Infused somehow during her fitful sleep with strange powers, Jane has nothing left to lose and a whole lot of people to make pay for what they've done! The survivors of the nuclear fire called the war Judgment Day lived only to face a new nightmare: the war against the machines! Dynamite presents the four-issue crossover event pitting Painkiller Jane against the Terminators in New York City (along with some future Terminator action!)!

Skynet sets out to perserve their (mostly) human-free future as writer Simon (Transformers) Furman and artist Nigel (Battlestar Galactica) Raynor unleash "Trial by Fire," the continuing adventures of the blockbuster Terminator franchise created by James Cameron and William Wisher!