Detroit, 2038. Lifelike androids have replaced the human workforce. They never tire, never disobey and never say “no”… until something changes. Some of them have started to behave irrationally, as if they were feeling emotions… Now you take control of three androids in their quest to discover who they really are.

Soon after the beginning of the game's introduction, the player begins the investigation in the Anekbah sector. He uncovers information that suggests the serial killer he is looking for is in fact not human but actually a demon. When members of an apparent underground, anti-government movement contact the player and confirm his suspicions, the investigation deepens and uncovers information; one of Omikron's chief police commanders, Commandant Gandhar, is a demon pretending to be human and lures human souls into Omikron from other dimensions by way of the Omikron video game. Kay'l 669 asking the player to help him was a trap: supposedly, if the in-game character dies, the real human playing the video game will lose their soul forever. Despite many assassination attempts on the protagonist's life by other demons working behind the scenes, the player destroys Gandhar with supernatural weaponry.